Are you interested in supplement research? If you are an adult aged 18+ years, you may be eligible to participate in a clinical trial investigating how well your body absorbs nutrients from different supplement formulations.
Please note: This page is a summary of the study outline and participant requirements. A full Participant Information Sheet with detailed information will be provided to you before you are asked to give your consent to participate.
Why is this study being conducted?
This study is being conducted by RDC Clinical to evaluate and compare the body’s ability to absorb nutrients from Food Grown formulations versus standard supplement formulations. Specifically, it compares Wild Nutrition Food-Grown Magnesium with standard magnesium bisglycinate, and Wild Nutrition Food-Grown B6 with standard Pyridoxal-5-phosphate (P5P). By measuring nutrient levels in your blood, we aim to better understand the bioavailability of these different formulations.
The nutrients being tested are essential for various aspects of health:
- Magnesium is the fourth most abundant mineral in your body and is essential for energy production in your cells (involved in over 300 enzymatic reactions), muscle and nerve function, blood sugar control, supporting immune function and reducing inflammation, and bone health
- Vitamin B6 is a water-soluble vitamin that is important for brain function and neurotransmitter production (serotonin, dopamine), protein metabolism and red blood cell formation, immune system support, and heart health
Although many individuals take vitamin and mineral supplements, their absorption can vary significantly depending on the formulation. Identifying which formulations are more efficiently absorbed may help people make better-informed choices about their supplement use and optimise the potential health benefits.
Wild Nutrition’s Food Grown technology is an innovative method of nutrient delivery that integrates vitamins and minerals into a whole-food matrix. By presenting nutrients in a form the body recognises as food, this approach may enhance absorption and utilisation compared to standard synthetic formulations.
Through this research, we aim to determine which supplement formulations offer superior bioavailability—meaning they enable the body to absorb and utilise a greater proportion of the nutrients provided.
How long is the study, and when does it start?
Your participation in this study will involve attending two full-day visits and two follow-up visits at the RDC Clinical site in Fortitude Valley. Each full-day visit will last approximately 6 to 9 hours, while each follow-up visit will take about 30 minutes.
We will confirm the specific dates of your clinic visits during your initial phone screening.
All requirements of the study will be completed during your clinic visit. There are no overnight stays required and you will not be required to take any study product at home.
Please see below for more information. You can also register your interest using the form at the bottom of this page.
There are 2 Study Arms available to choose from:
Arm 1 Vitamin B6
Round 1
- Thursday 15th January 2026 – approximately 7 hrs from 7am to approximately 2pm
- Friday 16th January 2026 – approximately 30 mins between 7am-9am
Round 2
- Thursday 29th January 2026 – approximately 7 hrs from 7am to approximately 2pm
- Friday 30th January 2026 – approximately 30 mins between 7am-9am
You will need to attend both study rounds.
- Wednesday 21st January 2026 – Approximately 9 hrs from 7am to approximately 4pm
- Thursday 22nd January 2026 – approximately 30 mins between 7am-9am
Round 2
- Wednesday 28th January 2026 – Approximately 9 hrs from 7am to approximately 4pm
- Thursday 29th January 2026 – approximately 30 mins between 7am-9am
About the product you’ll help investigate…
About the product you’ll help investigate…
This study is designed to evaluate how effectively your body absorbs nutrients from different supplement formulations. Specifically, we will compare Wild Nutrition Food Grown formulations with standard supplement formulations to determine which are more efficiently absorbed into the bloodstream.
We hypothesize that Wild Nutrition Food Grown formulations will demonstrate superior bioavailability compared to standard formulations, meaning your body may absorb more of the nutrients from the Food Grown products.
The products will be supplied in capsule form, and participants will be required to take the allocated study product at the beginning of each main study visit.
For each supplement you test:
- Wild Nutrition Food Grown formulation (nutrients incorporated into a whole food matrix)
- Standard formulation (conventional synthetic supplement)
This study uses a double-blind, crossover design, meaning you will receive both the Wild Nutrition version and the standard version during the trial, but neither you nor the investigators will know which product you are receiving at each visit. This design helps ensure that the results are not influenced by expectations about which product might work better.
An example of what your study involvement could be:
- 4 clinic visits over approximately 2 weeks
- Visit 1: 9-hour clinic visit (first formulation)
- Visit 2: 30-minute follow-up visit (24-hour blood draw)
- 1-week washout period
- Visit 3: 9-hour clinic visit (second formulation)
- Visit 4: 30-minute follow-up visit (24-hour blood draw)
During each session, you won’t know which product you’ve been allocated. However, this information will be available to you upon completion of the study or at any time if it is necessary for your care.
What is required of participants?
Your involvement in the study will be for one day (approximately 6-9 hours). There are no overnight stays required in this study, nor will you be required to take study product at home.
During the study, you will be asked to:
- Fast for 10 hours before your clinic visit (water is ok)
- Attend 4 clinic visits
- Take the study product (as capsules) once at the beginning of visit 1 and visit 3
- Have blood draws taken throughout visit 1 and visit 3 (via a cannula in your arm)
- Remain in the clinic for the duration of your visit for blood sampling
The information we collect during the study will enable the investigators to assess how well your body absorbs the different supplement formulations.
During visit 1 and visit 3, you will be provided with standardized meals (breakfast and lunch) and snacks, and you are welcome to bring your own device to pass the time. Please note that not all diets will be able to be catered to. If you do require a specific diet, please let us know at the time of screening. If you are planning to use your device, we do ask that participants to bring headphones so as not to disturb other participants.
Please note: This page is a summary of the study outline and participant requirements. A full Participant Information Sheet with detailed information will be provided to you before you are asked to give your consent to participate.
Compensation
Upon completion of the study requirements, you will be eligible for a payment of $500 for your time and travel expenses. The payment will be made by gift voucher or via direct deposit to your nominated bank account (your choice) once all study requirements have been met. Please note, that as payment needs to be processed after your completion and via our payment portal, please allow 5-7 business days after completion to receive payment.
Pro rata payments are also available in the case of early withdrawal as detailed in the participant information sheet that will be provided to you.
If you are interested in participating, we’d love to hear from you. Please register your interest by answering the questionnaire and completing the form on this page…we’ll then get in touch to screen you for eligibility.
Study location…
Our clinic is centrally located on Level 3, 252 St Pauls Terrace, Fortitude Valley.
Due to limited availability, there will not be on-site parking provided for this study. However, our clinic is a 10 minute walk from Fortitude Valley train station, and there are multiple bus stops within close proximity.
Check if you can register to take part…
- Adults 18+ years old
- BMI between 18.5 and 34.9 kg/m² (you can check your BMI using the calculator below)
- Generally healthy
- Able to provide informed consent
- Able to commit to completing the study requirements
- Able to fast for 10 hours prior to study visits
- Have not used magnesium or vitamin B6 supplements in the past 4 weeks
BMI Calculator
Please register your interest by answering the questionnaire and completing the form on this page… we’ll then get in touch to screen you for suitability.
Please note: This page is a summary of the study outline and participant requirements. A full Participant Information Sheet with more detailed information will be provided to you before you are asked to give your consent to participate.
Ethics approval & privacy
This clinical study has been approved by the University of Queensland Human Research Ethics Committee under Approval Number: 2025/HE001684. The study is also registered on the clinicaltrials.gov under Registration Number: ISRCTN12764003.
Trained trial coordinators will supervise your progress throughout the study. Your results will be made available to you at the conclusion of the study. Any of your personal information collected during the study will be kept in the strictest confidence.
